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Active Ingredient: Alfuzosin
Brand(s): Uroxatral

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What is Alfuzosin

Alfuzosin is an irregular antipsychotic medicine. Blocks dopamine receptors in the CNS and also competes with the dopamine button in the basal ganglia and the limbic system, both of which are components of the neonatal brain. It is used to treat hypersensitivity, hemopoietic system disorders (including anamnesis), alcoholic and harmful psychoses, myasthenia, and comas.

Alfuzosin Drug Uses

Alfuzosin is used to deal with the indicators and signs of benign enlargement of the prostate (benign prostatic hyperplasia, or BPH). Benign enlargement of the prostate is an issue that may happen in males as they get older. The prostate gland is situated under the bladder. As the prostate gland enlarges, certain muscle tissue within the gland might become tight and get in the way of the tube that drains urine from the bladder. This may result in urination issues, such as having to urinate frequently, a weak stream when urinating, or a feeling of not being able to completely empty the bladder.

Alfuzosin helps loosen up the muscle tissue within the prostate and the opening of the bladder. This might enhance the stream of urine or lower the signs. However, alfuzosin is not going to shrink the prostate. The prostate might proceed to get bigger. This might trigger the signs to get worse over time. So, even though alfuzosin might help with the problems caused by an enlarged prostate right now, surgery will still be needed at some point.

How long does it take for alfuzosin to start working?

How long will it take alfuzosin (Uroxatral) to work? Alfuzosin (Uroxatral) can start to relieve your BPH symptoms around 4 weeks after starting it. It’s important that you continue to take alfuzosin (Uroxatral), even if you don’t feel better right away.

Does Alfuzosin lower heart rate?

The heart rate did not change a lot because of alfuzosin; only a small increase was seen. In contrast, propranolol caused bradycardia, more marked in the upright position. Palpitations, headache, asthenia, and orthostatic hypotension were reported in the alfuzosin group.

Does alfuzosin help kidney stones?

The results confirmed the efficacy of tamsulosin and alfuzosin for distal ureteric stones. At the end of the study, 86.2% of patients taking tamsulosin and 76.7% of patients taking alfuzosin were able to expel their stones, compared to 50% of patients taking only analgesic.

What Should You Discuss To Your Doctor Before Using This Medicine

  1. Postural Hypotension: Postural hypotension with or without symptoms (e.g., dizziness) may develop within a few hours following administration of Alfuzosin. As with other alpha adrenergic antagonists, there is a potential for syncope. Patients should be warned of the possible occurrence of such events and should avoid situations where injury could result should syncope occur. There may be an increased risk of hypotension/postural hypotension and syncope when taking Alfuzosin concomitantly with anti-hypertensive medication and nitrates. Care should be taken when Alfuzosin is administered to patients with symptomatic hypotension or patients who have had a hypotensive response to other medications.

  2. Patients With Renal Impairment: Caution should be exercised when Alfuzosin is administered in patients with severe renal impairment (creatinine clearance < 30 mL/min).
  3. Patients With Hepatic Impairment: Alfuzosin is contraindicated for use in patients with moderate or severe hepatic impairment. Although the pharmacokinetics of Alfuzosin have not been studied in patients with mild hepatic impairment, caution should be exercised when Alfuzosin is administered to such patients.
  4. Prostatic Carcinoma: Carcinoma of the prostate and benign prostatic hyperplasia (BPH) cause many of the same symptoms. These two diseases frequently coexist. Therefore, patients thought to have BPH should be examined to rule out the presence of carcinoma of the prostate prior to starting treatment with Alfuzosin.

Uroxatral Drug Interactions

Although certain medicines shouldn’t be used collectively in any respect, in different instances, two totally different medicines could also be used collectively, even when an interaction may happen. In these instances, your physician might need to change the dose, or different precautions could also be mandatory. When you take this medication, it’s particularly vital that your healthcare professional know if you’re taking any of the medicines listed below. The following interactions were chosen based on how important they might be, but they are not necessarily all of them.

Using this medication with any of the next medicines shouldn’t be very helpful. Your physician might decide not to treat you with this medicine or change a number of the different medicines you are taking.

  • Atazanavir
  • Bepridil
  • Boceprevir
  • Cisapride
  • Clarithromycin
  • Cobicistat
  • Conivaptan
  • Darunavir
  • Dronedarone
  • Fluconazole
  • Fosamprenavir
  • Idelalisib
  • Indinavir
  • Itraconazole
  • Ketoconazole
  • Lopinavir
  • Mesoridazine

Other Interactions

Certain medicines shouldn’t be used at or across the time of consuming meals or consuming certain kinds of meals since interactions might happen. Using alcohol or tobacco with certain medicines may trigger conditions. The following interactions have been chosen on the premise of their potential significance and are usually not essentially all-inclusive.

Other Medical Problems Uroxatral

The presence of different medical issues might have an effect on using this medication. Make sure you inform your physician if you have any other medical issues, particularly:

  • Angina (chest ache) 
  • Heart rhythm issues
  • Postural hypotension 
  • Hypertension
  • Liver illness, average or extreme
  • Kidney illness
  • Liver illness

Proper Usage of Alfuzosin

  1. Take this medication precisely as directed by your physician. Do not take extra of it, don’t take it extra typically, and don’t take it for an extended time than your physician ordered.
  2. This medication comes with a affected person info leaflet. Read and observe these directions rigorously. Ask your physician if in case you have any questions.
  3. Take this medication with meals and with the identical meal each day.
  4. Swallow the extended-release pill entire. Do not break, crush, or chew it.

Alfuzosin Dosage

The dose of this medication can be totally different for various sufferers. Follow your physician’s orders or the instructions on the label. The following information consists solely of the common doses of this medication. If your dose is totally different, don’t change it until your physician tells you to take action.

The quantity of medication that you simply take will depend on the energy of the medication. Also, the variety of doses you are taking every day, the time allowed between doses, and the length of time you are taking the medication depend on the medical condition for which you might be using the medication.

  • For oral dosage kind (prolonged launch tablets):
    • For benign prostatic hyperplasia (BPH):
      • Adults: 10 milligrams (mg) as soon as a day.
      • Children: Use shouldn’t be really helpful.

Missed Dosage

If you miss a dose of this medication, take it as quickly as possible. But if it’s almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take double doses.

What is the best time to take Alfuzosin?

To avoid injury from dizziness or fainting, your doctor may tell you to take your first dose of alfuzosin with food at bedtime so that your body can get used to its effects. Take this medication regularly to get the most benefit from it. To help you remember, take it after the same meal each day.

Can I take alfuzosin after breakfast?

Alfuzosin should be taken just after eating food. This will make it easier for your body to absorb the medication. Take alfuzosin after the same meal each day. Do not take it on an empty stomach.

Can you drink on alfuzosin?

Your doctor may want to take your blood pressure from time to time, particularly when you first start the treatment. You are advised not to drink alcohol while you are on alfuzosin. Alcohol increases the risk of side effects from alfuzosin, such as feeling faint or dizzy.

Alfuzosin Storage

  1. Store the medication in a closed container at room temperature, away from warmth, moisture, and direct gentle. Keep from freezing.
  2. Keep out of the attain of youngsters.
  3. Do not preserve outdated medication or medication now not wanted.
  4. Ask your healthcare skilled how you need to eliminate any medication you don’t use.

Alfuzosin Precautions

It is essential that your physician examine your progress at your regular visits to ensure that this medication is working correctly and to examine for side effects.

  • Do not use this medication if you’re taking ketoconazole, itraconazole, or ritonavir.
  • Dizziness, lightheadedness, or fainting might happen after you utilize this medication, particularly once you rise up from a mendacity or sitting place. Getting up slowly might assist reduce this drawback. If you are feeling dizzy, lie down so you don’t faint. Then sit for just a few moments earlier than standing to stop the dizziness from returning.
  • This medication might trigger some individuals to change into dizzy or much less alert than they’re usually. Do not drive or do anything that could possibly be harmful till you understand how this medication impacts you.
  • Tell your eye physician (ophthalmologist) that you’ve used or are utilizing this medication earlier than cataract surgical procedure or every other eye process. This medication might trigger a critical eye drawback known as Intraoperative Floppy Iris Syndrome (IFIS).
  • Call your physician instantly if you happen to expertise a chronic erection. This is an especially uncommon facet impact, but when it goes untreated, can lead to everlasting erectile dysfunction (impotence).
  • Check along with your physician instantly if in case you have arm, again or jaw ache, chest ache or discomfort, chest tightness or heaviness, quick or irregular heartbeat, nausea, or sweating.
  • Benign prostatic hyperplasia can have the identical signs as prostate most cancers. They may typically happen collectively. Your physician might take a look at for the presence of the most cancers earlier than you begin utilizing this medication.
  • Do not take different medicines until they’ve been mentioned along with your physician. This consists of prescription or nonprescription (over-the-counter [OTC]) medicines and natural or vitamin dietary supplements.

Alfuzosin Side Effects

Along with its desired results, a medication might trigger some negative effects. Although not all of those uncomfortable side effects might happen, in the event that they do, you might want to seek medical attention.

Check in with your physician immediately if any of the following uncomfortable side effects happen:

  • Chest ache
  • chills
  • chilly sweats
  • confusion
  • fainting
  • quick, pounding, or irregular heartbeat or pulse
  • painful or extended erection of the penis

Other negative effects not listed can also happen to some sufferers. If you discover some other results, verify them with your healthcare professional. Call your physician for a medical recommendation about the drug’s negative effects.

Does Alfuzosin shrink the prostate?

Alfuzosin helps relax the muscles in the prostate and the opening of the bladder. This may help increase the flow of urine or decrease the symptoms. However, alfuzosin will not shrink the prostate. The prostate may continue to get larger.

Does Alfuzosin make you urinate more?

Alfuzosin helps relax the muscles in the prostate and the opening of the bladder. This may help increase the flow of urine or decrease the symptoms.

Does Alfuzosin cause dementia?

In the unadjusted cohort, 17.96%, 18.55, 20.64, 17.62, and 22.60% of people in the tamsulosin, doxazosin, terazosin, alfuzosin, and no-medication groups got dementia.


The information about psychotic disorders included in the Alfuzosin review is solely for educational purposes and should not be construed as an alternative to licenced healthcare or a referral to the well-being treatment distributor.


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Frequently asked questions

  1. What is Alfuzosin Uroxatral?

    In order to alleviate the discomfort caused by benign prostatic hyperplasia, the alpha-blocker known as alfuzosin is given to male patients who are undergoing treatment for the condition.

  2. What to do if you miss a dose?

    If you forget to take a dose of alfuzosin, you should take it as soon as you remember. However, if it is almost time for your next dose, you should skip the dose you missed and go back to your regular dosing schedule. You should never double your doses.

  3. What if u take too much Uroxatral?

    In the event that you experience an overdose, you should get in touch with either your primary care physician or the emergency room of the hospital that is located the closest to you. If necessary, you should also try to have a conversation with the poison control centre that is located within the hospital.

  4. How to store Alfuzosin?

    At a constant temperature of 77 degrees Fahrenheit (25 degrees Celsius), urexatral should be stored in a container that has a tight-fitting lid.

  5. What Should I Avoid While Taking Alfuzosin?

    You should avoid drinking alcohol or using illegal drugs while you are taking Uroxatral because doing so may reduce the benefits of the medication (for example, it may make your confusion even worse) and increase the adverse effects (for example, it may cause you to become more sedated).

  6. What are the side effects of Alfuzosin Uroxatral?

    The most common adverse reactions to this medication are drowsiness, dizziness, stomach pain, runny nose, headache, and fatigue. These side effects can occur in combination or alone.

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