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Active Ingredient: Plavix
Brand(s): Plavix

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What is Clopidogrel

Clopidogrel is an irregular antipsychotic medicine. blocks dopamine receptors in the CNS as well as conflicts dopamine buttons in basic gangliya as well as in limbic a component of the neoncephalon. It is used to treat hypersensitivity, disorders of the hemopoietic system (along with anamnesis), harmful psychosis in alcoholics, myasthenia, comas, and hypersensitivity.

Plavix Drug Uses

Clopidogrel is used alone or along with aspirin to reduce the possibility of a coronary heart assault or stroke. It is given to patients with acute coronary syndrome (ACS), to sufferers who’ve already had a coronary heart assault, extreme chest ache, or a stroke, or to sufferers with different circulation issues (e.g., peripheral arterial illness) that would trigger a stroke or coronary heart assault. Acute coronary syndrome is a situation where the blood flow to the heart is blocked.

A coronary heart attack or stroke might happen when a blood vessel is blocked by a blood clot. Clopidogrel is a platelet inhibitor. It lowers the chance that a dangerous blood clot will form by stopping platelets in the blood from sticking together. Clopidogrel may enhance the possibility of great bleeding in some individuals.

What Should You Discuss To Your Doctor Before Using This Medicine

  1. General Risk Of Bleeding: P2Y12 inhibitors (Thienopyridines), including Clopidogrel, increase the risk of bleeding. P2Y12 inhibitors (Thienopyridines), inhibit platelet aggregation for the lifetime of the platelet (7-10 days). Because the half-life of clopidogrel active metabolite is short, it may be possible to restore hemostasis by administering exogenous platelets; however, blood transfusions within 4 hours of the loading dose or 2 hours of the maintenance dose may be less effective.

  2. Discontinuation Of Clopidogrel: Discontinuation of Plavix increases the risk of cardiovascular events. If Clopidogrel must be temporarily discontinued (e.g., to treat bleeding or for surgery with a major risk of bleeding), restart it as soon as possible. When possible, interrupt therapy with Plavix for five days prior to such surgery. Resume Clopidogrel as soon as hemostasis is achieved.

  3. Thrombotic Thrombocytopenic Purpura (TTP): TTP, sometimes fatal, has been reported following use of Clopidogrel, sometimes after a short exposure. TTP is a serious condition that requires urgent treatment including plasmapheresis (plasma exchange). It is characterized by thrombocytopenia, microangiopathic hemolytic anemia (schistocytes [fragmented RBCs] seen on peripheral smear), neurological findings, renal dysfunction, and fever.

  4. Cross-Reactivity Among Thienopyridines: Hypersensitivity including rash, angioedema or hematologic reaction has been reported in patients receiving Clopidogrel, including patients with a history of hypersensitivity or hematologic reaction to other thienopyridines.

Clopidogrel Drug Interactions

Although sure medicines shouldn’t be used collectively in any respect, in different instances, two totally different medicines could also be used collectively, even when an interplay may happen. In these instances, your physician might need to change the dose or different precautions could also be mandatory. When you take this medication, it’s particularly vital that your healthcare professional know if you’re taking any of the medicines listed under. The following interactions were chosen based on how important they might be, but they are not necessarily all of them.

Using this medication with any of the following medicines shouldn’t be really helpful. Your physician might decide to not deal with you with this medicine or change a number of the different medicines you are taking.

  • Defibrotide

Using this medication with any of the following medicines is normally not really helpful, but could also be required in some instances. If each medicine is prescribed collectively, your physician might change the dose or how often you use one or each of the medicines.

  • Aceclofenac
  • Acemetacin
  • Alfentanil
  • Alipogene Tiparvovec
  • Alteplase, Recombinant
  • Amiodarone
  • Amlodipine
  • Amtolmetin Guacil
  • Anagrelide
  • Anileridine
  • Apalutamide
  • Apixaban
  • Ardeparin
  • Argatroban
  • Aspirin
  • Bemiparin

Other Interactions

Certain medicines shouldn’t be used at or across the time of consuming meals or consuming certain kinds of meals since interactions might happen. Using alcohol or tobacco with certain medicines may trigger conditions to happen. The following interactions have been chosen on the premise of their potential significance and are usually not essentially all-inclusive.

Using this medicine with any of the following is usually not a good idea, but it may not always be possible to avoid. If used collectively, your physician might change the dose or how frequently you use this medication, or offer you particular directions about meals, alcohol, or tobacco.

  • Grapefruit Juice

Other effects of Plavix

If you have other health problems, they might affect how you use this medicine. Make certain you inform your physician if you have any other medical issues, particularly:

  • Bleeding
  • Intracranial hemorrhage
  • Stroke
  • Transient ischemic assault

Proper Usage of Clopidogrel

Take this medication exactly as directed by your physician. Clopidogrel is not going to work correctly if you happen to take much less of it than directed. Taking more clopidogrel than prescribed may increase the risk of serious side effects while not improving outcomes.

  • This medication comes with a Medication Guide. It is essential that you simply learn and perceive this info. Be certain to ask your physician about something you don’t perceive.
  • You might take this medication with or with out meals.
  • If you might be additionally taking omeprazole (Prilosec®) or esomeprazole (Nexium®), don’t use it on the similar time that you simply take this medication. Talk along with your physician about utilizing a special antacid.
  • Your physician might let you know to take aspirin if you are utilizing clopidogrel. Do not change the dose or cease taking the aspirin with out speaking to your physician first.

Clopidogrel Dosage

The dose of this medication can be totally different for various sufferers. Follow your physician’s orders or the instructions on the label. The following information consists solely of the common doses of this medication. If your dose is totally different, don’t change it until your physician tells you to.

The quantity of medication that you simply take will depend on the energy of the medication. The variety of doses you are taking every day, the time allowed between doses, and the length of time you are taking the medication depend on the medical drawback for which you might be utilising the medication.

  • For oral dosage kind (tablets):
    • For prevention of coronary heart assault or stroke in sufferers with acute coronary syndrome (ACS):
      • Adults: At first, 300 milligrams (mg) taken as a single dose. Then, a upkeep dose of 75 mg as soon as a day. Your physician may offer you aspirin along with this medication.
      • Children: Use and dose should be decided by your physician.
    • For prevention of coronary heart assault or stroke in sufferers with a historical past coronary heart assault, stroke, or peripheral arterial illness:
      • Adults: 75 milligrams (mg) as soon as a day.
      • Children: Use and dose should be decided by your physician.

Missed Dosage

If you miss a dose of this medication, take it as soon as possible. But if it’s almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not double the doses.

Plavix Storage

  1. Store the medication in a closed container at room temperature, away from warmth, moisture, and direct gentle. Keep from freezing.
  2. Keep out of the attain of youngsters.
  3. Do not preserve outdated medication or medication now not wanted.
  4. Ask your healthcare skilled how you need to eliminate any medication you don’t use.

Clopidogrel Precautions

It is essential that your physician examine your progress at regular checkups. This will enable your physician to see if the medication is working correctly and to determine if you ought to proceed to take it. Blood assessments could also be wanted to examine side effects. The following things you can do more to prevent the negative effects:

  • Your physician might do a genetic check earlier than prescribing this medication to find out if you have a deficiency in a liver enzyme known as CYP2C19. This medication might not work as well if you have this situation.
  • Tell all the medical doctors, dentists, nurses, and pharmacists you visit that you’re taking this medication. Clopidogrel might enhance the chance of great bleeding throughout a surgical procedure, different medical procedures (e.g., coronary stent process), or some sorts of dental work. You might have to cease utilising this medication at the very least 5 days before a surgical procedure, medical process, or dental work. Do not cease taking your medication without your physician’s permission.
  • While you might be utilising this medication, if you have any form of bleeding, it could take longer than usual to cease, particularly if you happen to harm yourself. Stay away from tough sports or different conditions where you might be bruised, mutilated, or injured. Be cautious when using sharp objects, such as razors and fingernail clippers.

This medication might enhance your probability of bleeding or bruising. Consult your doctor right away if you notice any unusual bleeding or bruising, black, tarry stools, blood in your urine or stools, or pinpoint pink spots on your skin. Avoid picking your nostrils. If you could blow your nostril, blow it gently.

Clopidogrel Side Effects

Along with its wanted results, a medication might trigger some negative effects. Although not all of those uncomfortable side effects might happen, in the event that they do happen, they might want medical consideration.

Check with your physician immediately if any of the following uncomfortable side effects happen:

  • Collection of blood underneath the pores and skin
  • deep, darkish purple bruise
  • itching, ache, redness, or swelling
  • Bloody nostril
  • bloody, black, or tarry stools
  • vomiting of blood or materials that appears like espresso grounds

Other negative effects not listed can also happen in some sufferers. If you discover some other results, verify them with your healthcare professional. Call your physician for a medical recommendation about any negative effects.


Information concerning psychotic disorders, included within the review of Clopidogrel, is used for the informative features exclusively and should not be thought of as an alternative to licenced healthcare or referral of the well-being treatment distributor.


⚠Disclaimer of liability

This website isn\’t connected with any brands. They own all the brand, logos, and images. This website\’s content is for informational purposes only and not intended as medical advice, diagnosis, or treatment. If you have questions about a medical issue, consult a doctor. Do not reject medical advice or delay in getting it because of this website.

We do not sell medications on this website and instead direct visitors to reliable Internet service providers. So, we save you money, give you the best price, and make it easy and legal for you to get this medicine.

Frequently asked questions

  1. What is Clopidogrel Plavix?

    Plavix is used to diminish the risk of heart attacks and strokes caused by blood clots is increased in patients with a recent history of stroke, heart attack and peripheral vascular disease. It is used to prevent ischemic disorders like myocardial infarction, stroke, thrombosis of peripheral arteries and others.

  2. What to do if you miss a dose?

    If you forget to take a dose of clopidogrel, you should take it as soon as you remember. However, if it is almost time for your next dose, you should skip the dose you missed and go back to your regular dosing schedule. Never double the amount of medication that you are supposed to take.

  3. What if u take too much Plavix?

    In the event of an overdose, contact your primary care physician or the emergency room of the hospital closest to you; you may require immediate medical attention. If necessary, you may also get in touch with the hospital’s poison control centre.

  4. How to store Clopidogrel?

    Tablets and capsules of Plavix need to be stored at room temperature, which ranges from 15 to 30 degrees Celsius (59 to 86 degrees Fahrenheit).

  5. What Should I Avoid While Taking Clopidogrel?

    While you are taking Plavix, you should abstain from drinking alcohol or using illegal drugs because doing so may lessen the benefits of the treatment (for example, it may make your confusion worse) and may increase the adverse effects (for example, it may make you more sedated).

  6. What are the side effects of Clopidogrel Plavix?

    The most common adverse reactions include bleeding in the stomach or the intestinal tract, a hemorrhagic stroke, neutropenia, thrombocytopenia, abdominal pain, dyspepsia, gastritis, constipation, ulcers in the gastrointestinal tract, diarrhoea, and allergic reactions. Other less common adverse reactions include neutropenia, thrombocytopenia, and neutropenic fever.

  7. What are the Contraindication?

    Hypersensitivity, severe liver failure, acute bleeding, ulcer of the stomach or duodenum, ulcerous colitis, tuberculosis and other diseases that predispose a person to bleeding, pregnancy, breastfeeding, and the neonatal period are all risk factors.

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