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Active Ingredient: Cyproheptadine
Brand Name: Periactin

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What is Periactin

Periactin is an irregular antipsychotic medicine. Blocks dopamine receptors in the CNS and also competes with the dopamine button in the basal ganglia and the limbic system, both of which are components of the neonatal brain. It is used to treat hypersensitivity, hemopoietic system disorders (including anamnesis), alcoholic and harmful psychoses, myasthenia, and comas.

Common use

Periactin is a tablet that acts as a histamine and serotonin antagonist. It is prescribed in the treatment of anorexia, with exhaustion caused by a lack of appetite.

Periactin is an antidote to serotonin and histamine, and it can also make you feel hungry. This feature provokes the mass use of the drug, not for its intended purpose but as a means to increase weight, especially in patients suffering from muscle loss associated with AIDS, cancer, or other debilitating diseases.

As a result, the drug is used to treat allergic diseases (acute and chronic urticaria, serum sickness, pollinosis, vasomotor rhinitis, contact dermatitis, neurodermatitis, angioedema, allergic reactions to medication, and so on), as well as migraine (due to the anti-serotonin effect), loss of appetite of various etiologies (neurogenic anorexia, chronic diseases, and so on). Since histamine and serotonin cause the pancreas to make more juice, it has been suggested that Periactin could be used as part of a complex treatment for chronic pancreatitis.

This medication is used to:

  • Deal with allergic reactions and pruritus
  • Relieve migraines and vascular sorts of complications.

This medication belongs to a bunch of medicines referred to as antihistamines. It works by competing for receptor sites with serotonin and histamine.

Ask your physician if you have any questions about why this medication has been prescribed for you. Your physician could have prescribed it for an additional purpose. There may not be sufficient data to advocate the use of this medication for kids under the age of two years.

How to use Periactin?

  • Swallow the tablets complete with a full glass of water.
  • Proceed taking your medication for so long as your physician tells you.

What Should You Discuss To Your Doctor Before Using This Medicine

  • Don’t take PERIACTIN in case you have an allergy to:
    • any medication containing cyproheptadine
    • any of the substances listed on the finish of this leaflet.
    • some other comparable medicines
    • A few of the signs of an allergic response could embrace:
      • shortness of breath
      • wheezing or problem respiration
      • swelling of the face, lips, tongue or different components of the physique
      • rash, itching or hives on the pores and skin
  • Don’t breast-feed if you’re taking this medication.
    • The lively ingredient in PERIACTIN could cross into breast milk and there’s a risk that your child could also be affected.
  • Don’t give this medication to a toddler underneath the age of two years.
    • Security and effectiveness in kids youthful than 2 years haven’t been established.
  • Don’t give this drug to new child or untimely infants.
    • Use in infants has been related to apnoea, cyanosis, and respiratory problem. This drug shouldn’t be utilized in new child or untimely infants.
  • Don’t take this medication if you’re identified with:
    • angle-closure glaucoma
    • stenosing peptic ulcer
    • symptomatic prostatic hyper trophy
    • bladder neck obstruction
    • pyloroduodenal obstruction
  • Don’t take this medication if you’re:
    • struggling an acute asthmatic assault
    • aged or debilitated
    • endeavor monoamine oxidase inhibitor remedy
  • Don’t take this medication after the expiry date printed on the pack or if the packaging is torn or reveals indicators of tampering.
    • If it has expired or is broken, return it to your pharmacist for disposal.

If you’re unsure whether or not it’s best to begin taking this medication, discuss this with your physician.

Things you need to inform to your physician

  • Inform your physician in case you have allergic reactions to some other medicines, meals, preservatives or dyes.
  • Inform your physician in case you have or have had any of the next medical circumstances:
    • decrease respiratory tract signs together with these of acute bronchial asthma
    • blood dyscrasias
    • bronchial bronchial asthma
    • hyperthyroidism
    • heart problems
    • hypertension
  • Inform your physician if you’re pregnant or plan to grow to be pregnant or are breast-feeding.
    • Your physician can talk about with you the dangers and advantages concerned.

If you have not advised your physician about any of the above, inform them sooner than when you begin taking periactin.

Dosage and direction

Periactin dosage and intake Adults are prescribed 12-1 tablet 3-4 times per day or 1-2 teaspoons of syrup 3-4 times per day to increase appetite; children aged 2-6 years are prescribed no more than 2 tablets or 4 teaspoons of syrup per day; and children aged 6-14 years are prescribed no more than 3 tablets or 6 teaspoons of syrup per day.

Drowsiness, dry mouth, and, in rare cases, anxiety, ataxia, dizziness, nausea, and skin rash are all possible periactin side effects. Observe all instructions given to you by your physician or pharmacist fastidiously. They could differ from the knowledge contained in this leaflet. If you don’t perceive the directions on the field, ask your physician or pharmacist for assistance.

Your physician could alter the dose in line with your response.

  • Allergic reactions and pruritus
    • Adults: Take 1 pill, 3 occasions a day, as required. Don’t take greater than 8 tablets in 24 hours.
    • Youngsters (7 – 14 years): Take 1 pill, 3 occasions a day as required. Don’t take greater than 4 tablets in 24 hours.
    • Youngsters (2 – 6 years): Give half pill, two to 3 occasions a day. Don’t give greater than 3 tablets in 24 hours.
  • Migraine and vascular sorts of complications
    • Adults: Take 1 pill initially. If required, take a second pill after half-hour. Don’t take greater than 2 tablets each 4-6 hours.

Missed Dosage

  • Don’t take a double dose to make up for the dose that you just missed. This may increasingly improve the prospect of you getting an undesirable aspect impact.
  • If you’re unsure what to do, ask your physician or pharmacist.

Possible side effect

Inform your physician or pharmacist as quickly as possible if you don’t really feel well while you’re taking periactin. This medication helps most individuals with allergic reactions, pruritus, migraines, and vascular complications; however, it might have undesirable side effects in just a few individuals. All medicines can have negative effects. Generally, they’re critical, but more often than not, they don’t seem to be. You might want medical consideration if you happen to get one of the negative effects.

If you are over the age of 65, you may be more likely to experience negative effects. Don’t be alarmed by the next list of negative effects. You may not be an expert in any of them. Ask your physician or pharmacist to reply to any questions you might have.

They may include an allergic reaction.

  • hives;
  • difficulty breathing;
  • swelling of your face, lips, tongue, or throat.

Also, the most possible side effects include:

  • confusion, hallucinations, unusual thoughts or behaviour;
  • seizure (convulsions);
  • ringing in your ears;
  • feeling like you might pass out;
  • fast or pounding heartbeats;
  • easy bruising or bleeding; urinating less than usual or not at all;
  • or pale or yellowed skin, dark coloured urine, fever, or unusual weakness.

Less serious include:

  • mild drowsiness, dizziness, or spinning sensation;
  • restlessness or excitability (especially in children);
  • sleep problems (insomnia), tired feeling; numbness or tingly feeling;
  • increased sweating or urination;
  • blurred vision;
  • appetite changes;
  • dry mouth or nose, upset stomach;
  • or nausea, diarrhoea, constipation.

If you experience one of them, stop using Periactin and tell your doctor as soon as possible. Also, consult with your doctor about any side effect that seems unusual.

Inform your physician or pharmacist if you happen to discover any of the following, which they usually fear:

  • Pores and skin rash, extreme perspiration or photosensitivity
  • Sedation, sleepiness, dizziness, confusion
  • Restlessness, pleasure, insomnia, irritability or aggressive behavior
  • Dryness of nostril, mouth and throat
  • Nausea, vomiting, diarrhoea or constipation

The above listing consists of the extra-widespread negative effects of your medication.

Inform your doctor as soon as possible if you notice any of the following:

  • urinary retention points
  • jaundice
  • blurred imaginative and prescient

The above listing consists of critical negative effects that will require medical consideration.

If any of the following occur, inform your physician immediately or go to Accident and Emergency at your nearest hospital:

  • anaphylactic shock
  • convulsions
  • hallucinations
  • points respiration
  • elevated or uncommon heartrate, akin to palpitations

Periactin Storage

  • Preserve your tablets within the pack till it’s time to take them. In case you take the tablets out of the pack, they might not preserve nicely.
  • Preserve your tablets in a cool dry place the place the temperature stays beneath 30°C.
  • Don’t retailer PERIACTIN or some other medication within the lavatory or close to a sink. Don’t depart it on a window sill or within the automobile. Warmth and dampness can destroy some medicines.
  • Preserve it the place kids can’t attain it. A locked cabinet not less than one-and-a-half metres above the bottom is an effective place to retailer medicines.

Disposal: In case your physician tells you to cease taking this medication or the expiration date has passed, ask your pharmacist what to do with any medication that’s left over.

Periactin Precautions

  • Issues you could do
    • If you’re about to be began on any new medication, remind your physician and pharmacist that you’re taking PERIACTIN.
    • Inform some other docs, dentists and pharmacists who deal with you that you’re taking this medication.
    • If you’ll have surgical procedure, inform the surgeon or anaesthetist that you’re taking this medication.
      • It might have an effect on different medicines used throughout surgical procedure.
    • In case you grow to be pregnant whereas taking this medication, inform your physician instantly.
    • If you’re about to have any blood assessments, inform your physician that you’re taking this medication.
      • It might intervene with the outcomes of some assessments.

  • Issues you could not do
    • Don’t take PERIACTIN to deal with some other complaints except your physician tells you to.
    • Don’t give your medication to anybody else, even when they’ve the identical situation as you.

  • Issues to watch out of
    • Watch out driving or working equipment till you understand how PERIACTIN impacts you.
      • This medication could trigger drowsiness in some individuals. When you have any of those signs, don’t drive, function equipment or do anything that may very well be harmful. Drowsiness could proceed the next day. Youngsters ought to be cautious when using bicycles or climbing tree.
    • Watch out when ingesting alcohol while you’re taking this medication.
      • PERIACTIN could improve the results of alcohol. Alcohol ought to be averted while utilizing this medication.

Drug interaction

Periactin interacts with such medications as isocarboxazid (Marplan); phenelzine (Nardil); rasagiline (Azilect); selegiline (Eldepryl, Emsam); or tranylcypromine (Parnate). Also, note that the interaction between two medications does not always mean that you must stop taking one of them. As usual, it affects the effects of drugs, so consult with your doctor about how their interactions are being managed or should be managed.

Inform your doctor or pharmacist if you are taking any other medications, including any that you obtained without a prescription from a pharmacy, grocery store, or health food store. Some medicines and periactin could interfere with one another. These embrace:

  • Monoamine oxidase inhibitors used to deal with despair akin to phenelzine and tranylcypromine
  • Central nervous system depressants used to deal with nervousness, panic and sleep problems akin to hypnotics, sedatives, tranquilisers and anti-depressant medicine

These medicines could also be affected by periactin or have an effect on how well it really works. You might want completely different quantities of your medicines, or you could have to take completely different medicines. Your physician and pharmacist have extra information on medicines to watch out for or stay away from while taking this medication.


The information about psychotic disorders included in the Periactin review is solely for educational purposes and should not be construed as an alternative to licenced healthcare or a referral to the well-being treatment distributor.

⚠Disclaimer of liability

This website isn\’t connected with any brands. They own all the brand, logos, and images. This website\’s content is for informational purposes only and not intended as medical advice, diagnosis, or treatment. If you have questions about a medical issue, consult a doctor. Do not reject medical advice or delay in getting it because of this website.

We do not sell medications on this website and instead direct visitors to reliable Internet service providers. So, we save you money, give you the best price, and make it easy and legal for you to get this medicine.

Frequently asked questions

  1. What is Periactin?

    Periactin is a medication that comes in the form of tablets and acts as an antagonist of both histamine and serotonin. It is prescribed for the treatment of anorexic conditions, which are characterised by extreme fatigue brought on by a loss of appetite.

  2. What to do if you miss a dose?

    If you forget to take a dose of Periactin, you should take it as soon as you remember. However, if it is almost time for your next dose, you should skip the dose you missed and go back to your regular dosing schedule. You should never double your doses.

  3. What if u take too much Periactin?

    In the event of an overdose, contact your primary care physician or the emergency room of the hospital closest to you; you may require immediate medical attention. If necessary, you may also get in touch with the hospital’s poison control centre.

  4. How to store Periactin?

    Keep your medications out of the reach of light and moisture at a temperature ranging from 68 to 77 degrees Fahrenheit (20 to 25 degrees Celsius).

  5. What Should I Avoid While Taking Periactin?

    Avoid alcoholic beverages because they can make drowsiness worse. Alcohol, sedatives, and tranquillizers can also make drowsiness worse. Excitation may occur, especially in children. Use caution when operating machinery or driving a motor vehicle.

  6. What are the side effects of Periactin?

    Hives, difficulty breathing, and swelling of the face, lips, tongue, or throat are some of the potential adverse reactions that could occur.

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