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Brand(s): Nexium

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What is Esomeprazole?

Esomeprazole is an irregular antipsychotic medicine. blocks dopamine receptors in the CNS as well as conflicts dopamine buttons in basic gangliya as well as in limbic a component of the neoncephalon. It is taken for hypersensitivity, disorders of the hemopoietic system (along with anamnesis), alcoholic as well as harmful psychoses, myasthenia, and comas.

Nexium Drug Uses

Esomeprazole is used to deal with situations where there may be an excessive amount of acid in the abdomen. It is used to treat duodenal and gastric ulcers, erosive esophagitis, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome, a situation whereby the abdomen produces an excessive amount of acid.

Esomeprazole can also be used with antibiotics (e.g., amoxicillin, clarithromycin) to deal with ulcers that might be attributable to the H. pylori microorganism. This medication can also be used to stop abdominal ulcers and abdominal irritation in sufferers taking NSAIDs (e.g., aspirin, ibuprofen) for lengthy intervals of time. Esomeprazole is a proton pump inhibitor (PPI). It works by reducing the quantity of acid that’s produced by the abdomen.

What Should You Discuss With Your Doctor Before Using This Medicine?

  1. Presence of Gastric Malignancy: In adults, symptomatic response to therapy with Nexium I.V. does not preclude the presence of gastric malignancy. Consider additional follow-up and diagnostic testing in adult patients who have had a suboptimal response or an early symptomatic relapse after completing treatment with a PPI. In older patients, consider also having an endoscopy.
  2. Acute Interstitial Nephritis: Acute interstitial nephritis has been observed in patients taking PPIs, including Nexium I.V. Acute interstitial nephritis may occur at any point during PPI therapy and is generally attributed to an idiopathic hypersensitivity reaction. Discontinue Nexium I.V. if acute interstitial nephritis develops.
  3. Published observational studies suggest that PPI therapy like Nexium may be associated with an increased risk of Clostridium difficile-associated diarrhea, especially in hospitalised patients. This diagnosis should be considered for diarrhoea that does not improve. Patients should use the lowest dose and shortest duration of PPI therapy appropriate to the condition being treated.
  4. Several published observational studies suggest that proton pump inhibitor (PPI) therapy may be associated with an increased risk of osteoporosis-related fractures of the hip, wrist, or spine. The risk of fracture was increased in patients who received high-dose, defined as multiple daily doses, and long-term PPI therapy (a year or longer). Patients should use the lowest dose and shortest duration of PPI therapy appropriate to the condition being treated. Patients at risk for osteoporosis-related fractures should be managed according to established treatment guidelines.
  5. Cutaneous And Systemic Lupus Erythematosus: Cutaneous lupus erythematosus (CLE) and systemic lupus erythematosus (SLE) have been reported in patients taking PPIs, including esomeprazole. These events have occurred as both new onsets and exacerbations of existing autoimmune diseases. The majority of PPI-induced lupus erythematosus cases were CLE.

Esomeprazole Drug Interactions

Although certain medicines shouldn’t be used collectively in any respect, in different instances, two totally different medicines could also be used collectively, even when an interaction may happen. In these instances, your physician might need to change the dose or different precautions could also be mandatory. When you take this medication, it’s particularly vital that your healthcare professional know if you’re taking any of the medicines listed under. The following interactions have been chosen on the premise of their potential significance and are usually not essentially all-inclusive.

Using this medication with any of the following medicines shouldn’t be very helpful. Your physician might decide to not treat you with this medicine or change a number of the different medicines you are taking.

  • Rilpivirine

Using this medication with any of the following medicines is normally not very helpful, but could also be required in some instances. If each medicine is prescribed collectively, your physician might change the dose or how often you use one or each of the medicines.

  • Acalabrutinib
  • Amphetamine
  • Atazanavir
  • Belumosudil
  • Belzutifan
  • Benzphetamine
  • Bosutinib
  • Capecitabine
  • Cilostazol

Other Interactions

Certain medicines shouldn’t be used at or across the time of consuming meals or consuming certain kinds of meals since interactions might happen. Using alcohol or tobacco with certain medicines may trigger conditions. The following interactions have been chosen on the premise of their potential significance and are usually not essentially all-inclusive.

Using this medication with any of the following might trigger an elevated threat of certain uncomfortable side effects, which could also be unavoidable in some instances. If used collectively, your physician might change the dose or how typically you use this medication, or offer you particular directions about how to use meals, alcohol, or tobacco.

  • Cranberry

Nexium side-effects

If you have other health problems, they might affect how you use this medicine. Make certain you inform your physician if you have any other medical issues, particularly:

  • Diarrhea
  • Hypomagnesemia (low magnesium within the blood)
  • Osteoporosis (thinning of the bones)
  • Seizures
  • Vitamin B12 deficiency
  • Liver illness

Usage of Esomeprazole

Take this medication exactly as directed by your physician. Take no more of it, no more frequently, and no for a longer period of time than your doctor has prescribed.

This medication comes with a medication guide and the affected person’s directions. Read and observe the directions rigorously. Ask your physician if you have any questions.

Take this medication at the very least 1 hour before a meal and for the complete course of treatment, even if you start to really feel better after just a few days.

If you take this medication to deal with an ulcer attributable to an H. pylori infection, take it along with the antibiotics (e.g., amoxicillin, clarithromycin) at a similar time of day.

To use the capsule:

  • Swallow the capsule entire. Do not crush or chew it.
  • If the capsule can’t be swallowed, open it and sprinkle the contents on one tablespoon of applesauce.
  • Swallow the combination instantly. Do not chew or crush the granules.

To use the capsule with a nasogastric (NG) tube:

  • Open the capsule, empty the granules right into a 60 mL catheter-tipped syringe, and blend it with 50 mL of water.
  • Shake the syringe nicely for 15 seconds.
  • Inject or pour the combination into the nasogastric tube.
  • Refill the syringe with a small quantity of water and shake.
  • Flush the tube to rinse the entire medication into the abdomen.

To use the oral suspension:

  • Empty the contents of a 2.5 mg or 5 mg packet right into a container with 5 mL of water.
  • Empty the contents of a ten mg, 20 mg, or 40 mg packet right into a container with 15 mL of water.
  • Stir and leave it for two to three minutes to thicken.
  • Stir nicely and drink within half an hour.
  • If any medication remains after consuming, add extra water, stir, and drink instantly.

To use the oral suspension with a nasogastric or gastric tube:

  • Add 5 mL of water to a catheter-tipped syringe and add the contents of a 2.5 mg or 5 mg packet.
  • Add 15 mL of water to a catheter-tipped syringe and add the contents of a ten mg, 20 mg, or 40 mg packet.
  • Shake the syringe instantly and leave it for two to three minutes to thicken.
  • Shake the syringe once more and inject or pour the combination into the tube within half an hour.
  • Refill the syringe with 15 mL of water and shake.
  • Flush the tube to rinse the entire medication into the abdomen.

Esomeprazole Dosage

The dose of this medication can be totally different for various sufferers. Follow your physician’s orders or the instructions on the label. The following information consists solely of the common doses of this medication. If your dose is totally different, don’t change it until your physician tells you to.

The quantity of medication that you simply take will depend on the energy of the medication. The variety of doses you are taking every day, the time allowed between doses, and the length of time you are taking the medication depend on the medical drawback for which you might be using the medication.

  • For oral dosage varieties (capsules or suspension):
    • To stop NSAID-associated gastric ulcers:
      • Adults: 20 or 40 milligrammes (mg) as soon as a day for as much as 6 months. Your physician might alter your dose if wanted.
      • Children’s use and dose should be decided by your physician.
    • To deal with duodenal ulcers with H. pylori infection:
      • Adults: 40 milligrammes (mg) as often as once a day for 10 days. The dose is normally taken along with amoxicillin and clarithromycin. Your physician might alter your dose as desired.
      • Children’s use and dose should be decided by your physician.
    • To deal with erosive esophagitis:
      • Adults: 20 or 40 milligrammes (mg) as soon as a day for four to eight weeks. Your physician might alter your dose as desired. To stop erosive esophagitis from coming again, your physician might want you to take 20 mg as soon as a day for as long as 6 months.
      • Children 12 to 17 years of age: 20 or 40 milligrammes (mg) as early as possible for four to eight weeks. Your physician might alter your dose as desired.
      • Children 1 to 11 years of age and weighing 20 kilogrammes (kg) or more: 10 or 20 mg as soon as a day for 8 weeks. Your physician might alter your dose as desired.
      • Children 1 to 11 years of age and weighing less than 20 kg: 10 mg as soon as a day for 8 weeks. Your physician might alter your dose as desired.
      • Children 1 month to less than 12 months of age and weighing more than 7.5 kg to 12 kg: 10 mg as soon as a day for as much as 6 weeks. Your physician might alter your dose as desired.
      • Children 1 month to less than 12 months of age and weighing more than 5 kg to 7.5 kg should take 5 mg as soon as a day for as much as 6 weeks. Your physician might alter your dose as desired.
      • Children 1 month to less than 1 year of age and weighing 3 kg to 5 kg: 2.5 mg as soon as a day for as much as 6 weeks. Your physician might alter your dose as desired.
      • Infants younger than 1 month of age: use and dose should be decided by your physician.
    • To deal with gastroesophageal reflux illness (GERD):
      • Adults: 20 milligrammes (mg) as often as once a day for 4 weeks. Your physician might alter your dose as desired.
      • For children 12 to 17 years of age, 20 milligrammes (mg) as soon as a day for 4 weeks. Your physician might alter your dose as desired.
      • Children 1 to 11 years of age: 10 milligrammes (mg) as soon as a day for as much as 8 weeks. Your physician might alter your dose as desired.
      • Children younger than 1 year of age: Use and dose should be decided by your physician.
    • To deal with Zollinger-Ellison syndrome,
      • Adults: 40 milligrammes (mg) 2 times a day. Your physician might alter your dose as desired.
      • Children’s use and dose should be decided by your physician.
  • For oral dosage kind (delayed-release 24 hour capsules):
    • To deal with heartburn
      • Adults: 20 milligrammes (mg) as often as once a day for 14 days.
      • Children’s use and dose should be decided by your physician.

Missed Dosage

If you miss a dose of this medication, take it as soon as possible. But if it’s almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not double the doses.

Nexium Storage

  1. Store the medication in a closed container at room temperature, away from warmth, moisture, and direct light. Keep from freezing
  2. Keep out of the attainment of youngsters.
  3. Do not preserve outdated medication or medication now not wanted.
  4. Ask your healthcare professional how you need to eliminate any medication you don’t use.

Esomeprazole Precautions

It is essential that your physician examine you or your child’s progress at regular visits. This will let your doctor check to see if the medicine is working right and decide if you should keep taking it. Blood, urine, and different laboratory assessments could also be examined for negative effects. If your situation doesn’t improve or if it turns worse, examine it with your physician.

This medication is usually given along with amoxicillin (Amoxil®) and clarithromycin (Biaxin®) to deal with ulcers attributable to H. pylori infection. Be certain you understand the dangers and correct use of every other medicine your physician prescribes.

Consult your doctor right away if you experience a change in frequency or quantity of urination, blood in the urine, fever, joint aches, loss of appetite, nausea, pores and skin rash, swelling of the body, feet, or ankles, unusual tiredness or weakness, or unusual weight gain after using this medication. These could be signs of acute tubulointerstitial nephritis, a serious kidney problem.

Taking this medication for an extended period of time may make it more difficult for your body to absorb vitamin B12. Tell your physician if you have issues with a vitamin B12 deficiency.

This medication might trigger diarrhoea, and in some instances, it may be extreme. Do not take any medication to deal with diarrhoea without first checking with your physician. Check with your physician immediately if you have a watery stool that doesn’t go away, an abdominal ache, or a fever while taking this medication.

This medication might increase your risk of getting fractures of the hip, wrist, and backbone. This is especially true if you’re 50 years of age or older, use excessive doses, or use it for one year or more. Call your physician immediately if you have an extreme bone ache or are unable to walk or sit normally.

This medication might trigger hypomagnesemia (low magnesium within the blood). This is more likely to happen if you’re using this medication for more than 12 months or if you’re using it along with digoxin (Lanoxin®) or certain diuretics (water drugs). Check with your physician immediately if you have:

  • convulsions (seizures)
  • a quick, racing, or uneven heartbeat
  • muscle spasms (tetany).
  • tremors
  • uncommon tiredness or weak point

Esomeprazole Side Effects

Along with its desired results, a medication might trigger some negative effects. Although not all of those uncomfortable side effects might happen, in the event that they do, you might want medical consideration.

Check with your physician immediately if any of the following uncomfortable side effects happen:

  • Blistering, peeling, or loosening of the pores and skin
  • bloating
  • chills
  • constipation
  • cough
  • darkened urine
  • A problem with swallowing
  • dizziness
  • drowsiness
  • quick heartbeat
  • fever
  • indigestion
  • joint or muscle ache

Other negative effects not listed can also happen in some sufferers. If you discover some other results, verify them with your healthcare professional. Call your physician for a medical recommendation about any negative effects.

Disclaimer

The information about psychotic disorders included in the Esomeprazole review is solely for educational purposes and should not be construed as a substitute for licenced healthcare or a referral to the well-being treatment distributor.

 

Disclaimer of liability

This website isn\’t connected with any brands. They own all the brand, logos, and images. This website\’s content is for informational purposes only and not intended as medical advice, diagnosis, or treatment. If you have questions about a medical issue, consult a doctor. Do not reject medical advice or delay in getting it because of this website.

On this website we do not sell any medications and refer visitors to trusted Internet providers. In this way, we save you and the best price for many people, and you can easily and legally obtain this powerful medicine.

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Frequently asked questions

  1. What is Esomeprazole Nexium?

    Nexium is a treatment for gastroesophageal reflux disease and stomach ulcers that acts as a specific inhibitor of a proton pump (PPIs) found in the parietal cells of the mucous layer of the stomach.

  2. What to do if you miss a dose?

    If you forget to take a dose of esomeprazole, you should take it as soon as you remember. However, if it is almost time for your next dose, you should skip the dose you missed and go back to your regular dosing schedule. You should never double your doses.

  3. What if u take too much Nexium?

    In the event that you experience an overdose, contact your primary care physician or the emergency room of the hospital that is closest to you. If necessary, you may also wish to speak with the hospital’s poison control centre.

  4. How to store Esomeprazole?

    Keep the temperature between 59 and 77 degrees Fahrenheit (15 and 25 degrees Celsius), and keep it out of the reach of light and moisture, as well as children and pets.

  5. What Should I Avoid While Taking Esomeprazole?

    You should abstain from drinking alcohol or using illegal drugs while you are taking Nexium because doing so could reduce the benefits of the medication (such as making your confusion worse) and increase the negative effects (such as sedation) of the medication.

  6. What are the side effects of Esomeprazole Nexium?

    Patients who have a rash may experience a headache, diarrhoea, nausea, abdominal pain, flatulence (gas), constipation, or dry mouth in addition to symptoms of an allergy such as hives and swelling of the throat and face. Patients may also have an allergic reaction.

  7. What are the Contraindication?

    Hypersensitivity to Nexium or any other benzimidazole medication, including but not limited to mebendazole (Vermox) and albendazole (Albenza), as well as in patients being treated with atazanavir, in children younger than 12 years of age.

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