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What is Nolvadex or Tamoxifen?
Nolvadex was originally marketed to slow the growth of breast cancer. Estrogen causes the cancer to grow faster here, and nolvadex blocks the action of estrogen, slowing the growth. Tamoxifen citrate is itself a very mild estrogen which binds very strongly to the estrogen receptors, it binds much more strongly than the more violent estrogen variants.
How does Nolvadex or Tamoxifen work?
As a result, it occupies the estrogen receptors so that stronger estrogens cannot do their job. It should also be noted that nolvadex (and also Clomid)) is a SERM (selective estrogen receptor modulator), it does not prevent the formation of estrogen as aromatase inhibitors (Proviron, arimidex, letrozole, exemestane) do. In addition, nolvadex causes an increase in LH (Luteinizing Hormone) and FSH (Follicle Stimulating Hormone). These two hormones, especially LH, cause the body to produce more testosterone._
Nolvadex can be used in several ways
Nolvadex can be used in three ways: firstly, it can be used by female athletes to increase performance and achieve a dry look, secondly, it can be used during a course to prevent gynecomastia, and finally, it is a very good tool for recovering after a course and restarting your own hormone production.
- For the first only a low dose needs to be used, 10 mg per day is enough. The same applies to the second method of use. When gynecomastia occurs during a treatment 10 to 20 mg of nolvadex per day should be started quickly. After the symptoms have disappeared the use of nolvadex should be continued for another 4 days or so.
- For this purpose Nolvadex is better than Clomid because it has a stronger effect. When taking extremely aromatizing anabolics a stronger agent like arimidex is also needed, but nolvadex should be taken during the first few days because arimidex (and the other aromatase inhibitors: letrozole and exemestane) only work after a few days.
How long should you use Nolvadex?
How long Nolvadex should be used and which dose should be taken during the follow-up treatment depends on the course. As a rule of thumb, during the first half of the course the dose should be twice as high as during the second half. 2 weeks 40 mg per day followed by 2 weeks 20 mg per day is sufficient for most courses.
- The course of treatment is started 2 weeks after the last injection for long esters, 4 days to a week after the last injection for short esters and the day after the last intake for pills. The post-treatment period then lasts 3 to 5 weeks, depending on the length of the esters and suppression of the body’s own testosterone production by the drugs taken.
- The normal side effects that are sometimes experienced with nolvadex are acne and headaches, nausea and vomiting, and hot flashes. In women, irregular menstruation may occur. Also, women should be careful not to become pregnant while using nolvadex because nolvadex interferes with the functioning of the pill (birth control).
- Furthermore, the package insert lists a number of side effects such as excessive sweating, dizziness, disturbed bowel function, hair loss, skin rashes, leg cramps, fluid retention (paradoxical to the effect of Nolvadex), insufficient blood flow to the heart and blood vessels and formation of blood clots that can lead to an embolism.
- Keep in mind that Nolvadex is a drug to inhibit the growth of breast cancer and is therefore often taken by women for long periods of time. It is precisely with long-term use that the most serious side effects occur. With a follow-up course of up to 6 weeks or with the prevention of gynecomastia during a course, virtually no side effects will be experienced.
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Frequently asked questions
Nolvadex contains the substance tamoxifen citrate. This is a mild form of estrogen that has no major estrogenic side effects. This estrogen binds strongly on the estrogen receptors. This is why the powerful estrogens can no longer bind and therefore become inactive in the body. Tamoxifen is also known to increase LH (Luteinizing Hormone) and FSH (Follicle Stimulating Hormone). LH in particular can potentially increase the production of testosterone in the body. Look at all the different types of Nolvadex here.
There are possible side effects of Nolvadex use, but we will see that this is a very well tolerated SERM for most men and women. However, there are possible side effects, but they are generally very rare. Most men do not have the first problem. The side effects of Nolvadex will be slightly more common in women. The possible side effects of Nolvadex use include:
– Vaginal itching, bleeding, discharge or discomfort
– Hot flashes
– Upset stomach
The above are the most common side effects of Nolvadex. Other possible side effects of Nolvadex although less common than the above are:
– Decreased of white blood cells
– Endometrial changes
– Increased triglyceride levels
– Pulmonary embolism
It is important that you continue to take this medicine consistently. If you do forget a dose:
– If you are taking this medicine once a day: will it be more than 8 hours before you take the next dose as normal? Then take the forgotten dose. Will it be less than 8 hours? Then skip the forgotten dose.
– If you are taking this medicine twice a day: will it be more than 4 hours before you take the next dose as normal? If so, take the forgotten dose. Will it be less than 4 hours? Then skip the forgotten dose.
– If you are taking this medicine once a week, will it be more than 3 days (72 hours) before you take the next dose as normal? If so, take the forgotten dose. Will it be less than 3 days (72 hours) before you take the next dose? Then skip the forgotten dose.
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