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What is Zopiclone or Imovane?

Imovane contains the active ingredient Zopiclone, a cyclopyrrolone derivative, is a short-acting hypnotic agent. Zopiclone belongs to a novel chemical class which is structurally unrelated to existing hypnotics. The pharmacological profile of zopiclone is similar to that of the benzodiazepines.

Does Zopiclone work?

In sleep laboratory studies of 1 to the 21-day duration in man, zopiclone reduced sleep latency, increased the duration of sleep and decreased the number of nocturnal awakenings. Zopiclone delayed the onset of REM sleep but did not reduce consistently the total duration of REM periods.

  • The duration of stage 1 sleep was shortened, and the time spent in stage 2 sleep increased. In most studies, stage 3 and 4 sleep tended to be increased, but no change and actual decreases have also been observed. The effect of zopiclone on stage 3 and 4 sleep differs from that of the benzodiazepines which suppress slow-wave sleep. The clinical significance of this finding is not known.

How does Imovane help you sleep?

The brain naturally releases calming chemicals. One of these chemicals is called gamma-aminobutyric acid (GABA.) Zopiclone works by boosting the effects of GABA and this helps to calm the brain, enabling you to get to sleep.

How long will I sleep with Zimovane?

Extra care is needed when taking zopiclone because it can cause sleepiness and affect your concentration the next day. Drowsiness can last for at least 11 hours after taking your dose. Avoid alcohol while you are taking zopiclone, especially when you first start treatment.

How long does zopiclone make you sleepy?

Extra care is needed when taking Imovane because it can cause sleepiness and affect your concentration the next day. Drowsiness can last for at least 11 hours after taking your dose. Avoid alcohol while you are taking zopiclone, especially when you first start treatment.

Imovane Usage

Imovane is used to assist individuals over 18 years of age with sleeping difficulties, additionally referred to as insomnia. It could possibly show you how to go to sleep and to cut back the variety of occasions you get up in the course of the night time. It’s used for brief time period remedy (2-4 weeks) of insomnia. It isn’t really helpful to be used for greater than 4 weeks at a time. Your physician, nevertheless, could prescribe Imovane for an additional goal. Ask your physician in case you have any questions on why Imovane has been prescribed for you.

Can I take Zopiclone every night?

Imovane should be taken at the lowest dose possible for the shortest possible time. You may agree with your doctor not to take it every night, but perhaps every other night (alternate nights), so you do not get into the habit of taking it. You should take zopiclone just before going to bed.

What is a good substitute for Zimovane?

Eszopiclone, a stereoisomer of zopiclone, is a non-benzodiazepine hypnotic agent of the cyclopyrrolone family. Similar to zopiclone, eszopiclone is a synthetic compound shown to be effective in treating insomnia

Drug Interactions

You should inform your physician if you’re taking some other medicines, together with any that you just purchase and not using a prescription from a pharmacy, grocery store or well being meals retailer. Some medicines could intervene with the absorption of Imovane. These embrace:

  • medicines to deal with despair, nervousness and psychological sickness
  • St John’s wort, (hypericum), a natural treatment for despair
  • different medicines which can trigger drowsiness
  • benzodiazepines (medicines used as sedatives or to deal with nervousness)
  • ache relievers, akin to opioids or narcotic analgesics
  • alcohol, (ethanol), contained in some medicines eg cough syrups
  • muscle relaxants
  • antihistamines
  • medicines used to deal with epilepsy
  • antiviral remedy
  • rifampicin, erythromycin or clarithromycin (medicines used to deal with infections)
  • ketoconazole or itraconazole (medicines used to deal with fungal infections)

These medicines could also be affected by Imovane or could have an effect on how nicely it really works. You might have to take completely different quantities of your medication or completely different medicines. Your physician or pharmacist will advise you. Your physician or pharmacist has extra data on medicines to watch out with or to keep away from whereas taking Imovane.

Usage of Imovane

You should take Zopiclone just before going to bed. If you can make sure that you get seven to eight hours of uninterrupted sleep, you will probably experience fewer side effects the next day (such as poor memory). Imovane should be swallowed whole with a glass of water.

  1. Swallow the pill with a full glass of water.
  2. Take Imovane instantly earlier than you go to mattress. Imovane ought to be taken as a single consumption and never be re-administered throughout the identical night time.
  3. If you’re unsure when to take it, ask your physician or pharmacist.
  4. Imovane ought to solely be used for brief durations (eg 2 to 4 weeks). Steady long run use (i.e. longer than 4 weeks) isn’t really helpful.

How long does Zimovane take to peak?

Zopiclone is absorbed rapidly. Peak concentrations are reached within 1.5-2 hours and they are approximately 30ng/ml and 60ng/ml after administration of 3.75mg and 7.5mg respectively.

Dosage of Imovane

Each tablet contains 7.5 mg of zopiclone as the active ingredient. It also contains the inactive ingredients calcium hydrogen phosphate dihydrate, wheat starch (gluten), sodium starch glycollate, lactose monohydrate, magnesium stearate, hypromellose, titanium dioxide, macrogol 6000.

  • Imovane ought to solely be taken when you’ll be able to get a full night time’s sleep (7 to eight hours) earlier than it’s essential be lively once more.
  • The usual grownup dose of Imovane is one pill simply earlier than you go to mattress.
  • Imovane ought to be taken in a single consumption and never readministered throughout the identical night time.
  • If you’re over 65 years of age the dose is half a pill taken simply earlier than you go to mattress.
  • When you have a liver or kidney downside, the same old really helpful dose is half a pill taken simply earlier than you go to mattress.

Your physician could have prescribed a unique dose. Ask your physician if you’re not sure of the proper dose for you. They are going to inform you precisely how a lot to take. Observe the directions they offer you. In case you take the fallacious dose, Imovane could not work as nicely. Imovane shouldn’t be given to kids or adolescents lower than 18 years of age

Missed Dosage

In case you neglect to take the pill earlier than you go to mattress, and also you get up late within the night time or very early within the morning, don’t take it. You could have bother waking at your regular time.

Storage Zopiclone

  1. Preserve your tablets within the blister pack till it’s time to take them. In case you take the tablets out of the field or the blister pack they might not preserve nicely.
  2. Preserve the medication in a cool dry place the place the temperature stays beneath 25°C.
  3. Don’t retailer it or some other medication within the lavatory, close to a sink or on a windowsill. Warmth and dampness can destroy some medicines.
  4. Don’t depart it within the automobile. Warmth and damp can destroy some medicines.
  5. Preserve it the place kids can’t attain it. A locked cabinet not less than one-and-a-half metres above floor is an effective place to retailer medicines.

Disposal: In case your physician tells you to cease taking it, or the medication has handed its expiry date, ask your pharmacist what to do with any which can be left over. Return any unused medication to your pharmacist.

Imovane Precautions

Tell your doctor or pharmacist if you have allergies to:

  • Any other substances such as foods, dyes or preservatives.
  • Tell your doctor if you are pregnant or intend to become pregnant. Like most medicines of this kind, Imovane is not recommended to be used during pregnancy. Your doctor will discuss the risks and benefits of taking it if you are pregnant.
  • Tell your doctor if you are breastfeeding or planning to breastfeed. Your doctor will discuss the risks of taking it if you are breastfeeding or planning to breastfeed.
  • Tell your doctor if you have any problems with your breathing or if you often snore while you are asleep.

Tell your doctor if you have ever been addicted to alcohol or any drug or medicine, or if you have ever suffered from a mental illness. If you have, you may be at risk of getting into a regular pattern or habit of taking Imovane.

Do not take Imovane if you have:

  • Been drinking alcohol or you believe that you may have alcohol in your bloodstream;
  • Sleep apnoea (a condition where you temporarily stop breathing while you sleep);
  • Myasthenia gravis (a condition in which the muscles become weak and tire easily);
  • Severe liver problems;
  • Acute and/or severe lung problems;
  • Had a stroke.

Other precautions when you start using Zopiclone

  • Issues you could do
    • Inform all of the docs, dentists and pharmacists who’re treating you that you’re taking Imovane.
    • If you’re about to be began on any new medication, inform your physician and pharmacist that you’re taking Imovane.
    • In case you plan to have surgical procedure that wants a basic anaesthetic, inform your physician or dentist that you’re taking this medication.
    • In case you grow to be pregnant while you’re taking this medication, cease taking it and inform your physician or pharmacist instantly.

  • Issues you could not do
    • Don’t take greater than the really helpful dose except your physician tells you to. This could improve the danger of negative effects.
    • Don’t give this medication to anybody else, even when they’ve the identical situation as you.
    • Don’t use this medication to deal with some other complaints except your physician tells you to.
    • Don’t drink alcohol earlier than or after taking this medication. This could improve the danger of negative effects.

  • Issues to watch out of
    • As a result of Imovane will make you sleepy, you shouldn’t function harmful equipment or drive motor autos for 12 hours after you’re taking it. You also needs to watch out the subsequent morning while you get up.
      • Be sure you know the way you react to Imovane earlier than you drive a automobile or function equipment. This is essential if you’re taking different medicine that additionally make you drowsy.
      • Impairment can happen regardless of feeling absolutely awake, in absence of signs or if you’re feeling higher.
    • Watch out if you’re over 65 and unwell or taking different medicines. You might be extra delicate to among the negative effects of Imovane.
    • You shouldn’t drink alcohol while you’re taking Imovane. The consequences of alcohol may very well be made worse whereas taking Imovane.

Allergies and Imovane

Do not take Imovane if you are allergic to it or any of the ingredients listed here. Some symptoms of an allergic reaction include skin rash, itching, shortness of breath or swelling of the face, lips or tongue, which may cause difficulty in swallowing or breathing. Do not give Imovane to children or adolescents. There is no experience with its use in children or adolescents.

  • Do not take it if you are pregnant or intend to become pregnant. It may affect your developing baby if you take it during pregnancy. Your doctor will discuss the risks and benefits of taking it if you are pregnant.

Do not take it if you are breastfeeding or planning to breastfeed

Imovane passes into breast milk and there is a possibility your baby may be affected. Your doctor will discuss the risks and benefits of using it if you are breastfeeding or planning to breastfeed. Do not take Imovane after the expiry date (EXP) printed on the pack. If you take it after the expiry date has passed, it may not work as well. Do not take Imovane if the packaging is damaged or shows signs of tampering.

Imovane Side Effects

All medicines have some undesirable negative effects. Generally they’re critical, however more often than not they don’t seem to be. Your physician or pharmacist has weighed the dangers of utilizing this medication towards the advantages they anticipate it is going to have for you. Don’t be alarmed by this listing of potential negative effects. You might not expertise any of them.

Inform your physician if you happen to discover any of the next they usually fear you:

  • complications
  • dry mouth
  • bitter style in your mouth
  • drowsiness
  • heartburn
  • nausea, vomiting and/or diarrhoea
  • change in urge for food
  • abdomen ache
  • rash
  • agitation
  • despair
  • confusion
  • nervousness
  • dizziness
  • blurred imaginative and prescient
  • impotence
  • sleep strolling or different uncommon behaviours (akin to driving, consuming, making a cellphone name, or having intercourse and many others.) whereas not being absolutely awake, a few of which have been related to critical accidents and demise

Alcohol can improve the danger of sleep strolling or different behaviours akin to driving or consuming meals while asleep. This danger can also be elevated if you happen to take greater than the really helpful dose. Some sleep medicines could trigger a short-term reminiscence loss. When this happens, an individual could not keep in mind what has occurred for a number of hours after taking the medication.

That is normally not an issue since most individuals go to sleep after taking the medication. Sleep medicines ought to normally, be used just for quick durations of time. In case your sleep issues proceed, seek the advice of your physician.

Some medicines could cause dependence, particularly when they’re used often for longer than just a few weeks. Individuals who have been depending on alcohol or different medicine previously could have a better probability of turning into hooked on sleep medicines. When you have been hooked on alcohol or medicine previously, you will need to inform your physician earlier than beginning Imovane.

Disclaimer

Information concerning psychotic disorders, included within the review of Imovane, is used for the informative features exclusively as well as should not be thought-about to alternative to licensed healthcare or referral of the well being treatment distributor.

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Frequently asked questions

  • What is Imovane?

    Imovane contains the active ingredient zopiclone. Zopiclone, a cyclopyrrolone derivative, is a short-acting hypnotic agent. Zopiclone belongs to a novel chemical class which is structurally unrelated to existing hypnotics. 

  • What to do if you miss a dose?

    If you miss a dose of Imovane, take it as quickly as potential. However, whether it is virtually time to your subsequent dose, skip the missed dose and return to your common dosing schedule. Do not double doses.

  • What if u take too much of this drug?

    If an overdose happens, name your physician or call your nearest hospital. You might have pressing medical care. You might also contact the poison management at your local hospital.

  • How to store this medicine?

    Store your medicines at room temperature between 68-77 F (20-25 C) away from light and moisture. 

  • What Should I Avoid While Taking Imovane?

    Marked drowsiness may occur avoid alcoholic drinks alcohol, sedatives, and tranquillizers may increase drowsiness excitability may occur, especially in children be careful when driving a motor vehicle or operating machinery 

  • What are the side effects of this drug?

    The medication cannot be used in patients with hypersensitivity to the components of Imovane, in patients during acute recovery phase of myocardial infarction, and in patients treated by MAO inhibitors.


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